Live DataUpdated hourly

Hybrid Principal Software Engineer Jobs with Python

Filter Jobs

Market Insights for Jobs in Hybrid Principal Software Engineer with Python

Real-time data from 12 active listings in the last 30 days.

Active Roles

Avg. Salary

$223K

Top Hiring Companies

BioSpaceNiCEMITREIridiumMicrosoft AI

Principal Software Engineer

BioSpace

Hybrid

Posted: Sep 4, 2026

Thousand Oaks, CABe among the first 25 applicants

5+ years exp$153,130 - $181,766/yearFull Time

Pharma & Biotech

RPA

Blue Prism

UiPath

Power Automate

Machine Learning

Citizen Development

+28 more

View Details Apply Now

Principal Software Engineer

BioSpace

Hybrid

Posted: Sep 4, 2026

Tampa, FLBe among the first 25 applicants

5+ years exp$153,130 - $181,766/yearFull Time

Pharma & Biotech

RPA

Blue Prism

UiPath

Power Automate

Machine Learning

Citizen Development

+28 more

View Details Apply Now

Principal Software Engineer

Cboe Global Markets

Hybrid

Posted: Sep 2, 2026

Chicago, IL

12+ years exp$165,750 - $235,950/yearFull Time

Financial Services

Software & SaaS

Python

Django

React

Next.js

Tailwind CSS

JavaScript

+7 more

View Details Apply Now

Principal Software Engineer

NetApp

Hybrid

Posted: Aug 30, 2026

Vienna, VA

15+ years exp$220,000 - $372,000/yearFull Time

Software & SaaS

Hardware & Semiconductors

AWS

GCP

Azure

FaaS

PaaS

Node.js

+14 more

View Details Apply Now

Principal Software Engineer

Iridium

Hybrid

Posted: Aug 29, 2026

Chandler, AZBe among the first 25 applicants

10+ years exp$150,000 - $200,000/yearFull Time

Telecommunications

Aerospace & Defense

Python

pySerial

FastAPI

Pandas

NumPy

Airflow

+14 more

View Details Apply Now

Stop spending hours hunting for the right job posting.

New jobs like these get 200+ applicants within 24 hours. Let them come to you the minute they go live — straight to Telegram.

7-day free trial · No credit card required

Principal Software Engineer

Global X ETFs

Hybrid

Posted: Aug 21, 2026

New York, NYBe among the first 25 applicants

8+ years exp$230,000 - $245,000/yearFull Time

Financial Services

Java

Spring Boot

Python

AWS

Claude Code

Codex

+6 more

View Details Apply Now

Principal Software Engineer

David Joseph & Company

Hybrid

Posted: Aug 20, 2026

San Francisco, CABe among the first 25 applicants

10+ years exp$220,000 - $280,000/yearFull Time

Software & SaaS

GoLang

TypeScript

Python

AI/ML infrastructure

Distributed systems

Data pipelines

+2 more

View Details Apply Now

Principal Software Engineer

Plenful

Hybrid

Posted: Aug 20, 2026

San Francisco, CABe among the first 25 applicants

12+ years expFull Time

Software & SaaS

Healthcare

AWS

Postgres

Python

React

TypeScript

View Details Apply Now

Principal Software Engineer

Microsoft AI

Hybrid

Posted: Aug 19, 2026

Redmond, WABe among the first 25 applicants

6+ years exp$142,800 - $274,800/yearFull Time

Software & SaaS

C++

Java

JavaScript

Python

+2 more

View Details Apply Now

Principal Software Engineer

Harnham

Hybrid

Posted: Aug 18, 2026

San Francisco Bay AreaBe among the first 25 applicants

$280,000 - $350,000/yearFull Time

Software & SaaS

Media & Entertainment

Python

Django

React

AWS

PostgreSQL

OpenAI

View Details Apply Now

Hybrid Principal Software Engineer + Python Jobs by Location

San Francisco Chicago Mclean Va New York Redmond Wa Sandy Ut Tampa Fl Thousand Oaks Ca

24/7 job-alert agent

Don't miss the next hybrid Principal Software Engineer + Python job

Speed is everything. Get an instant alert the second a new hybrid position is posted.

Instant Telegram alerts·7-day free trial·No credit card required