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Remote Senior Principal Ai Engineer Jobs in Boston

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Real-time data from 1 active listings in the last 30 days.

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Avg. Salary

$235K

Top Hiring Companies

Vertex Pharmaceuticals

Senior Principal AI Engineer

Remote

Posted: Aug 22, 2026

Boston, MA27 applicants

No experience required$188,000 - $282,000/yearFull Time

Pharma & Biotech

AI/ML platform architecture

Generative AI systems and large language model integration

Agentic workflows and orchestration frameworks

Multi-agent or autonomous agent system design

Prompt engineering and prompt management

Workflow orchestration and automation

+15 more

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